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OCR: KH from During the course of efforts to isolate GI inn hypothalamic extracts, Krulich and McC elease fromdiscovered a fraction that inhibited GH r the fact pituitary incubates, in vitro. They name or) and ("growth hormone release inhibitory fact ed by a dualpostulated that GH secretion was regula Ther control system, one stimulator and the paid to inhibitory. Relatively little attention was was this concept when first described since it cific effect. thought by most workers to be a non-spe